High Blood Pressure Secondary to Polycystic Kidney Disease
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Posted On :
Jan-11-2012
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Article Word Count :
438
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High blood pressure is prevalent among elderly people in past. Whereas, it tends to affect young people nowadays. Elevated blood pressure could be primary or secondary, and massive clinical observations tell that high blood pressure can be a very prevalent complication secondary to Polycystic Kidney Disease (PKD).
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High blood pressure is prevalent among elderly people in past. Whereas, it tends to affect young people nowadays. Elevated blood pressure could be primary or secondary, and massive clinical observations tell that high blood pressure can be a very prevalent complication secondary to Polycystic Kidney Disease (PKD). Once elevated blood pressure occurres in patients with PKD, it usually indicates renal function aggravates from 2nd stage to 3rd stage of Chronic Kidney Disease in clinical diagnosis. If no proper measures on these cysts, elevated blood pressure will exacerbate further, and this can further decrease renal function.
The most dangerous factor of PKD is the enlarged cysts can press kidney, causing short supply of blood in kidneys. There is an automatic system in human body which can adjust the general blood pressure that is RAAS (rennin-angiotensin-aldosterone system). When the blood supply become insufficient, the jusxtaglomerular cells will secrete and synthesize rennin, which is a sort of acid protease. Rennin can promote the hydrolysis of proangiotensin existing in the plasma. The hydrolysate can be further decomposed by ACE (angiotensin-converting-enzyme) into angiotensin II, which can shrink the micro-arteries in human body, so that the blood pressure can be elevated.
Besides, angiotensin will be further hydrolyzed into antiogensin III under the function of ACE, and angiotensin III can activate the aldosterone which increases the reabsorption of Na+ and water by tubular and concentrated pipe, this can increase the blood volume in human body and cause further increase of blood pressure, If this pressure from cysts can not be adjusted, this high blood pressure secondary to polycystic kidney disease will not appear.
What treatment can be available now for this trouble?
Usually, patients would give some hypotensors like sublingual captopril or intravenous nicardipine for urgent high blood pressure. However, these method can not solve the problem from the root. Just as mentioned above, high blood pressure is caused by shortness of blood supply. So the key point to regulate high blood pressure for PKD patients is to halt the enlargement of cysts and reduce the pressure from cysts to renal parenchyma. By reducing the pressure of cysts, the aggravation of blood circulation can be blocked. Meanwhile, blood and nutrition supply in kidneys can be ameliorated by supplying effective components. Through massive clinical observations, Micro-Chinese Medicine Osmotherapy has definite effect to shrink cysts and improve ischemia and anoxia in kidneys. After a complete and strict treatment, hypertension induced by Polycystic Kidney Disease can be treated naturally and patients no longer depend on those hypotensor. If you have doubts about this article and seek more information about this treatment, you can email us at kidneytreat@hotmail.com.
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Article Source :
http://www.articleseen.com/Article_High Blood Pressure Secondary to Polycystic Kidney Disease_132343.aspx
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Author Resource :
High Blood Pressure Secondary to Polycystic Kidney Disease
Polycystic Kidney Disease
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Keywords :
Polycystic Kidney Disease, High Blood Pressure,
Category :
Disease And Illness
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Disease And Illness
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